Product ID:MARCAINE HYDROCHLORIDE
MSDS Date:05/07/1993
FSC:6850
NIIN:00F048759
MSDS Number: BZTWG

STERLING WINTHROP INC SANOFI WINTHROP PHARMACEU

90 PARK AVE
NEW YORK, NY 10016-1302
US

Emergency Phone: 212-907-2000/800-223-5511

Info Phone: 212-907-2000/800-223-5511

Cage: GO573

WINTHROP PHARMACEUTICALS

NEW YORK, NY 10156 US

Telephone: 212-907-2000

Cage: 63240

BUPIVACAINE HYDROCHLORIDE, MARCAINE HYDROCHLORIDE *96-2*

CAS: 14252-80-3

RTECS: TK6125000

BUPIVACAINE HYDROCHLORIDE

CAS: 18010-40-7

Fraction By Weight: <1%

WATER

CAS: 7732-18-5

RTECS: ZC0110000

Fraction By Weight: >25%

Routes of Entry: Inhalation:NO Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:OVERDOSE, MAY CAUSE ADVERSE CNS,
CARDIOVASCULAR SYSTEM, ALLERGIC & NEUROLOGICAL REACTIONS. SYSTEMIC
DOSE-RELATED TOXICITY, UNDERVENTILATION, APNEA & RESPIRATORY
PARALYSIS MAY OCCUR, WHICH CAN LEAD TO CARDIAC ARREST.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:RESTLESSNESS, ANXIETY, INCOHERENT SPEECH,
LIGHTHEADEDENESS, NUMBNESS, TINGLING OF THE MOUTH & LIPS, METALLIC
TASTE, TINNITUS, DIZZINESS, BLURRED VISION, TREMORS, TWITCHING,
DEPRESSION, DROWSINESS.

First Aid:EYES: FLUSH W/PLENTY OF WATER FOR 15 MINS. SKIN: WASH
THOROUGHLY W/SOAP & WATER. OBTAIN MEDICAL ATTENTION IN ALL CASES.
NOTE TO PHYSICIAN: DELAY IN PROPER DOSE-RELATED TOXICITY,
UNDERVENTILATION FROM ANY CAUSE &/ALTERED SENSITIVITY MAY LEAD TO
THE DEVELOPMENT OF ACIDOSIS, CARDIAC ARREST & POSSIBLY DEATH.

Extinguishing Media:USE ANY EXTINGUISHING AGENT SUITABLE FOR
SURROUNDING FIRE.
Fire Fighting Procedures:USE NORMAL FIRE FIGHTING GEAR.

Spill Release Procedures:USE RUBBER/PLASTIC GLOVES. CONTAIN BY PLACING
PAPER TOWELS/A SUITABLE ABSORBENT MATERIAL AROUND THE EDGES OF THE
AREA & WORK INWARD. CAREFULLY SCOOP UP INTO A PROPERLY LABELED
WASTE CONTAINER FOR DISP OSAL. WASH AREA TO REMOVE FROM SURFACES.

Handling and Storage Precautions:KEEP THIS & ALL DRUGS OUT OF THE REACH
OF CHILDREN.
Other Precautions:AVOID EYE CONTACT.

Respiratory Protection:NONE NORMALLY REQUIRED.
Ventilation:NORMAL
Protective Gloves:NONE NORMALLY REQUIRED.
Eye Protection:NONE NORMALLY REQUIRED.
Work Hygienic Practices:USE GOOD PERSONAL HYGIENE. WASH HANDS & EXPOSED
SKIN THOROUGHLY W/SOAP & WATER AFTER USE.
Supplemental Safety and Health

Solubility in Water:COMPLETE
Appearance and Odor:COLORLESS LIQUID

Stability Indicator/Materials to Avoid:YES

Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.